Hydrogen-bonding-promoted oxidative addition and regioselective arylation of olefins with aryl chlorides

The first, general and highly efficient catalyst system is developed that has allowed a wide range of activated and unactivated aryl chlorides to couple regioselectively with olefins. Ethylene glycol has played a double role in the arylation, which has facilitated oxidative addition and has promoted the subsequent dissociation of chloride from Pd(II) to produce a cationic Pd(II)-olefin species.