SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

Authors :: Barber, Matthew F.
Michishita-Kioi, Eriko
Xi, Yuanxin
Tasselli, Luisa
Kioist, Mitomu
Moqtaderi, Zarmik
Tennen, Ruth I.
Paredes, Silvana
Young, Nicolas L.
Chen, Kaifu
Struhl, Kevin
Garcia, Benjamin A.
Gozani, Or
Li, Wei
Chua, Katrin F.
Source :: Nature. July 5, 2012, Vol. 487 Issue 7405, p114, 7 p.
Publication Year :: 2012
Abstract: Sirtuin proteins regulate diverse cellular pathways that influence genomic stability, metabolism and ageing (1,2). SIRT7 is a mammalian sirtuin whose biochemical activity, molecular targets and physiological functions have been unclear. [...]