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Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

Authors :
Minden, Marcus Duhren-von
Ubelhart, Rudolf
Schneider, Dunja
Wossning, Thomas
Bach, Martina P.
Buchner, Maike
Hofmann, Daniel
Surova, Elena
Follo, Marie
Kohler, Fabian
Wardemann, Hedda
Zirlik, Katja
Veelken, Hendrik
Jumaa, Hassan
Source :
Nature. September 13, 2012, Vol. 489 Issue 7415, p309, 5 p.
Publication Year :
2012

Abstract

B-cell antigen receptor (BCR) expression is an important feature of chronic lymphocytic leukaemia (CLL), one of the most prevalent B-cell neoplasias in Western countries (1). The presence of stereotyped and [...]

Details

Language :
English
ISSN :
00280836
Volume :
489
Issue :
7415
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.302769499