Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability

Authors :: Zhu, Weiquan
London, Nyall R.
Gibson, Christopher C.
Davis, Chadwick T.
Tong, Zongzhong
Sorensen, Lise K.
Shi, Dallas S.
Guo, Jinping
Smith, Matthew C.P.
Grossmann, Allie H.
Thomas, Kirk R.
Li, Dean Y.
Source :: Nature. December 13, 2012, Vol. 492 Issue 7428, p252, 4 p.
Publication Year :: 2012
Abstract: The innate immune response is essential for combating infectious disease. Macrophages and other cells respond to infection by releasing cytokines, such as interleukin-1β (IL-1β), which in turn activate a well-described, [...]

Subjects :: Inflammation -- Mediators
Immune response -- Observations
Cellular signal transduction -- Research
Interleukins -- Testing
Environmental issues
Science and technology
Zoology and wildlife conservation

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