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IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity
- Source :
- Journal of Clinical Investigation. August 1, 2013, Vol. 123 Issue 8, p3383, 12 p.
- Publication Year :
- 2013
-
Abstract
- Background. Systemic administration of IL-12p70 has demonstrated clinical activity in cancer patients, but dose-limiting toxicities have hindered its incorporation in vaccine formulations. Here, we report on the immunological and clinical [...]
Details
- Language :
- English
- ISSN :
- 00219738
- Volume :
- 123
- Issue :
- 8
- Database :
- Gale General OneFile
- Journal :
- Journal of Clinical Investigation
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.341937532
- Full Text :
- https://doi.org/10.1172/JCI68395