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Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation
- Source :
- Nature Medicine. April 1, 2014, p350, 13 p.
- Publication Year :
- 2014
-
Abstract
- Kindlin-1 is an integrin tail binding protein that controls integrin activation. Mutations in the FERMT-1 gene, which encodes for Kindlin-1, lead to Kindler syndrome in man, which is characterized by [...]
- Subjects :
- Cell proliferation -- Physiological aspects -- Genetic aspects -- Research
Stem cells -- Genetic aspects -- Research -- Physiological aspects
Bone morphogenetic proteins -- Physiological aspects -- Genetic aspects -- Research
Transforming growth factors -- Physiological aspects -- Genetic aspects -- Research
Biological sciences
Health
Subjects
Details
- Language :
- English
- ISSN :
- 10788956
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.369247841