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Neonates, antibiotics and the microbiome
- Source :
- Nature Medicine. May 1, 2014, Vol. 20 Issue 5, p469, 2 p.
- Publication Year :
- 2014
-
Abstract
- As babies leave their mothers' wombs, they are colonized by commensal bacteria. A new study shows that these microbes in a newborn's gut can promote an increase in circulating neutrophils that can guard the body from infections. Altering a neonate's gut microbiota with perinatal antibiotic treatment can impair neutrophils, leaving the newborn vulnerable to attack by harmful bacteria (pages 524-530).<br />Globally, around 4 million newborn babies die yearly due to sepsis (1). Prolonged use of antibiotics is currently under clinical practice in the interest of preventing early-onset sepsis in newborns [...]
Details
- Language :
- English
- ISSN :
- 10788956
- Volume :
- 20
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.382233910