Clivorine, an otonecine pyrrolizidine alkaloid from Ligularia species, impairs neuronal differentiation via NGF-induced signaling pathway in cultured PC12 cells

Authors :: Xiong, Aizhen
Yan, Artemis Lu
Bi, Cathy W.C.
Lam, Kelly Y.C.
Chan, Gallant K.L.
Lau, Kitty K.M.
Dong, Tina T.X.
Lin, Huangquan
Yang, Li
Wang, Zhengtao
Tsim, Karl W.K.
Source :: Phytomedicine: International Journal of Phytotherapy & Phytopharmacology. August 15, 2016, p931, 8 p.
Publication Year :: 2016
Abstract: ABSTRACT Background: Pyrrolizidine alkaloids (PAs) are commonly found in many plants including those used in medical therapeutics. The hepatotoxicities of PAs have been demonstrated both in vivo and in vitro; [...]

Subjects :: Neurons -- Growth
Alkaloids -- Health aspects
Compositae -- Usage -- Health aspects
Company growth
Biological sciences
Health
Science and technology

Language :: English
ISSN :: 09447113
Database :: Gale General OneFile
Journal :: Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Publication Type :: Academic Journal
Accession number :: edsgcl.461128106
Full Text :: https://doi.org/10.1016/j.phymed.2016.06.006

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