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Safety and immunogenicity of HIV recombinant envelope vaccines in HIV-infected infants and children

Authors :
Lambert, John S.
McNamara, James
Katz, Samuel L.
Fenton, Terry
Kang, Minhee
VanCott, Thomas C.
Livingston, Robert
Hawkins, Elizabeth
Moye, Jack, Jr.
Borkowsky, William
Johnson, Daniel
Yogev, Ram
Duliege, Ann-Marie
Francis, Donald
Gershon, Anne
Wara, Diane
Martin, Natasha
Levin, Myron
McSherry, George
Smith, Gale
Source :
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. Dec 15, 1998, Vol. 19 Issue 5, p451, 11 p.
Publication Year :
1998

Abstract

AIDS vaccines made from the HIV gp120 or gp 160 protein appear to be safe enough to use in infants and children. Researchers vaccinated 72 HIV-infected children between one month and 18 years old with a gp120 vaccine, a gp160 vaccine, or a placebo approximately every month for about six months. Sixty-five percent of those who received the vaccine developed an immune response to it, which did not occur in the placebo group.

Details

ISSN :
10779450
Volume :
19
Issue :
5
Database :
Gale General OneFile
Journal :
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Publication Type :
Periodical
Accession number :
edsgcl.53525191