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Refined genetic mapping of the Darier locus to a <1-cM region of chromosome 12q24.1, and construction of a complete, high-resolution P1 artificial chromosome/bacterial artificial chromosome contig of the critical region

Authors :
Monk, Sarah
Sakuntabhai, Anavaj
Carter, Simon A.
Bryce, Steven D.
Cox, Roger
Harrington, Louise
Levy, Elaine
Ruiz-Perez, Victor L.
Katsantoni, Eleni
Kodvawala, Ahmer
Munro, Colin S.
Burge, Susan
Larregue, Marc
Nagy, Gyula
Rees, Jonathan L.
Lathrop, Mark
Monaco, Anthony P.
Strachan, Tom
Hovnanian, Alain
Source :
American Journal of Human Genetics. April, 1998, Vol. 62 Issue 4, p890, 14 p.
Publication Year :
1998

Abstract

Darier disease (DD), an autosomal dominant skin disorder involving loss of adhesion between epidermal cells and abnormal keratinization, has been studied in four families. Linkage analysis has shown key recombination events to refine the DD locus to a

Details

ISSN :
00029297
Volume :
62
Issue :
4
Database :
Gale General OneFile
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
edsgcl.54537009