Back to Search
Start Over
Impaired Mitochondrial Signaling for Insulin Secretion in Pancreatic [Beta]-cells of Bcl-[x.sub.L] Transgenic Mice
- Source :
- Diabetes. May, 1999, Vol. 48 Issue 5, SA248
- Publication Year :
- 1999
-
Abstract
- Transgenic mice with targeted over-expression of the anti-apoptotic protein Bc1-[x.sub.L] in pancreatic [Beta]-cells develop hyperglycemia due to deficient insulin secretion. Since Bc1-[x.sub.L] is present on mitochondrial membranes and affects mitochondrial [...]
- Subjects :
- Diabetes -- Research
Health
Subjects
Details
- ISSN :
- 00121797
- Volume :
- 48
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Diabetes
- Publication Type :
- Periodical
- Accession number :
- edsgcl.54776801