Media effects of antioxidant activities of phenols and catechols

The impact of numerous media on the capability of several categories of phenolic antioxidants were calculated using stopped flow methods in hexane, 1-propanol, tert-butyl alcohol and acetone. Reductions in the transfer from hexane to the hydrogen bond accepting solvents were credited to hydrogen bonding from the phenolic group. The catechol DTBC indicated a substantial decrease in activity in hydrogen bond accepting solvents. The antioxidant properties of alpha-tocopherol, 2,2,5,7,8-pentamethyl-6-hydroxychroman, catechol and 3,5-di-tert-butylcatechol were determined using the oxygen uptake method.