Back to Search Start Over

Development of a Multi-Product SE-UHPLC Method for the Determination of Size-Variants in Bispecific Antibody Formats

Authors :
Graf, Tobias
Ruppert, Raphael
Knaupp, Alexander
Hafenmair, Georg
Violini, Sebastien
Kiessig, Steffen
Haindl, Markus
Wegele, Harald
Leiss, Michael
Source :
LC-GC North America. December, 2018, Vol. 36 Issue 12, p870, 9 p.
Publication Year :
2018

Abstract

Elevated levels of aggregates in protein therapeutics are associated with an increased risk of triggering adverse immune responses in patients. It is thus of paramount importance to closely monitor these [...]

Subjects

Subjects :
Chemistry

Details

Language :
English
ISSN :
15275949
Volume :
36
Issue :
12
Database :
Gale General OneFile
Journal :
LC-GC North America
Publication Type :
Academic Journal
Accession number :
edsgcl.571516522