INTERFERON-[Gamma] PRIMES HUMAN ALVEOLAR MACROPHAGES FOR INCREASED INTERLEUKIN-1Β RELEASE BY DECREASING BIOAVAILABLE IRON

Authors :: Hays, Steven R.
Blumer, B M.
O'Brien-Ladner, A R.
Source :: Chest. October 1999, Vol. 116 Issue 4, 265S
Publication Year :: 1999
Abstract: Purpose: It has been demonstrated that decreasing intracellular iron levels by chelation with deferoxamine (DFA), increases the release of IL-1Β from LPS-stimulated human alveolar macrophages (AM). IFN-[Gamma] has also been [...]

Subjects :: Iron in the body -- Physiological aspects
Interferon gamma -- Physiological aspects
Deferoxamine -- Physiological aspects
Health
Physiological aspects

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