Interaction between Abeta(1-42) and Abeta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro

Authors :: Hasegawa, Kazuhiro
Yamaguchi, Itaru
Omata, Saburou
Gejyo, Fumitake
Naiki, Hironobu
Source :: Biochemistry. Nov 23, 1999, Vol. 38 Issue 47, p15514, 8 p.
Publication Year :: 1999
Abstract: Results from in vitro experiments indicate that beta-amyloid fibril formation is dependent on the fresh peptide components added to the reaction than on the preexisting fibrils. A model for the interaction between the peptides is presented.

Subjects :: Alzheimer's disease -- Research
Amyloidosis -- Research
Fluorescence spectroscopy -- Methods
Aging -- Molecular aspects
Biological sciences
Chemistry

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