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Hepatitis B virus transgenic mouse model of chronic liver disease

Authors :
Larkin, Jonathan
Clayton, Marcy
Sun, Bill
Perchonock, Claire E.
Morgan, Judith L.
Siracusa, Linda D.
Michaels, Frank H.
Feitelson, Mark A.
Source :
Nature Medicine. August, 1999, Vol. 5 Issue 8, p907, 6 p.
Publication Year :
1999

Abstract

The development of a mouse model of hepatitis B-induced chronic liver disease is reported. Transgenic mice were produced using cloned hepatitis B virus DNA in mice that had severe combined immunodeficiency.

Details

ISSN :
10788956
Volume :
5
Issue :
8
Database :
Gale General OneFile
Journal :
Nature Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.59220757