Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

Authors :: Le Hir, Herve
Moore, Melissa J.
Maquat, Lynne E.
Source :: Genes & Development. May 1, 2000, Vol. 14 Issue 9, p1098, 11 p.
Publication Year :: 2000
Abstract: Evidence for stable association of proteins at exon-exon junctions is discussed relative to pre-mRNA splicing. The splicing has been shown to change mRNP composition. Several proteins that associate with mRNA exon-exon junctions only as a result of splicing were found through use of a novel in vitro crosslinking approach.

Subjects :: Meiosis -- Research
Mitosis -- Research
Messenger RNA -- Research
Exon (Molecular genetics) -- Research
Molecular genetics -- Research
RNA splicing -- Research
Proteins -- Crosslinking
Biological sciences

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