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Waiting for anaphase: Mad2 and the spindle assembly checkpoint

Authors :
Shah, Jagesh V.
Cleveland, Don W.
Source :
Cell. Dec 22, 2000, Vol. 103 Issue 7, p997, 4 p.
Publication Year :
2000

Abstract

The review discusses regulation of the cell cycle events with particular reference to anaphase stage of cell division. Data point out that Mad2 protein possessing ubiquitination and proteolytic machinery participates in the signal transmission for the spindle checkpoint.

Subjects

Subjects :
Cell cycle -- Physiological aspects
Spindle (Cell division) -- Physiological aspects
Proteins -- Bioavailability
Cellular signal transduction -- Physiological aspects
Anaphase -- Analysis
Biological sciences

Details

ISSN :
00928674
Volume :
103
Issue :
7
Database :
Gale General OneFile
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
edsgcl.69073740

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