Pi-aromatic and sulfur nucleophilic partners in cationic pi-cyclizations: intramolecular amidoalkylation and thioamidoalkylation cyclization via omega-carbinol lactams

Research has been conducted on the ring closure reactions. Results indicate that these reactions proceed via a nicleophilic attack of the electron pi-aromatic or the lone sulfur atom pair onto the endo- or exocyclic N-acyliminium ions generated from the omega-carbinol lactams under acidic conditions.