Straightforward asymmetric entry to highly functionalized medium-sized rings fused to beta-lactams via chemo- and stereocontrolled divergent radical cyclization of Baylis-Hillman adducts derived from 4-oxoazetidine-2-carbaldehydes

Research has been conducted on the chiral nonracemic bicyclic beta-lactams. The straightforward synthesis of these beta-lactams has been performed via the Baylis-Hillman reaction of 4-oxoazetidine-2-carbaldehydes with free radicals and the results are presented.