The metal ion binding properties of calreticulin modulate its conformational flexibility and thermal stability

Authors :: Li, Zhenjie
Stafford, Walter F.
Bouvier, Marlene
Source :: Biochemistry. Sept 18, 2001, Vol. 40 Issue 37, p11193, 9 p.
Publication Year :: 2001
Abstract: Research has been conducted on the soluble chaperone calreticulin. The structural properties of the human calreticulin affected by the calcium and zinc ions have been investigated via analytical ultracentrifugation, proteolysis and circular dichroism and the results are discussed.

Subjects :: Biochemistry -- Research
Metal ions -- Physiological aspects
Calcium ions -- Physiological aspects
Zinc -- Physiological aspects
Proteolysis -- Analysis
Circular dichroism -- Analysis
Ions -- Analysis
Biological sciences
Chemistry

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