One-pot synthesis of difluoroaldols from acylsilanes and trifluoromethyltrimethylsilane. Application to the synthesis of a difluoro analogue of egomaketone

Authors :: Lefebvre, Olivier
Brigaud, Thierry
Portella, Charles
Source :: Journal of Organic Chemistry. March 23, 2001, Vol. 66 Issue 6, p1941, 6 p.
Publication Year :: 2001
Abstract: Research has been conducted on the difluoroaldol compounds. The synthesis of these compounds has been carried out in a one-pot procedure and the involvement of the acylsilane, trifluoromethyltrimethylsilane and aldehyde is discussed.

Subjects :: Chemistry, Organic -- Research
Silane -- Physiological aspects
Fluorine -- Physiological aspects
Amides -- Physiological aspects
Carbonyl compounds -- Physiological aspects
Aldehydes -- Physiological aspects
Biological sciences
Chemistry

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