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Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion

Authors :
Burcelin, Remy
Thorens, Bernard
Source :
Diabetes. June 2001, Vol. 50 Issue 6, p1282, 8 p.
Publication Year :
2001

Abstract

[GLUT2.sup.-/-] mice reexpressing GLUT1 or GLUT2 in their β-cells (RIPGLUT1 x [GLUT2.sup.-/-] or RIPGLUT2 x [GLUT2.sup.-/-] mice) have nearly normal glucose-stimulated insulin secretion but show high glucagonemia in the fed [...]

Details

Language :
English
ISSN :
00121797
Volume :
50
Issue :
6
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.80392815