Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis

Authors :: Gulick, Andrew M.
Schmidt, Dawn M.Z.
Gerlt, John A.
Rayment, Ivan
Source :: Biochemistry. Dec 25, 2001, Vol. 40 Issue 51, p15716, 9 p.
Publication Year :: 2001
Abstract: Three-dimensional structure analysis of two L-Ala-D/L-Glu epimerases from Escherichica coli and Bacillus subtilis shows significant size differences between them but similar active site architecture.

Subjects :: Microbial enzymes -- Analysis
Enzymes -- Structure-activity relationship
Crystals -- Structure
Binding sites (Biochemistry) -- Analysis
Peptidoglycans -- Physiological aspects
Biological sciences
Chemistry

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