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Whole blood and freeze-dried plasma in Canadian trauma care

Authors :
Dion, Pierre-Marc
Mack, Johnathan
Alam, Asim
Vuong, Sebastian
Scott, Jeff
Miller, Damien
Beckett, Andrew
Source :
Canadian Journal of Surgery. October, 2024, Vol. 67 Issue 5, pE349, 3 p.
Publication Year :
2024

Abstract

This article highlights the crucial role of blood transfusion in trauma care and explores the historical and contemporary use of whole blood and freeze-dried plasma in Canadian health care. Early use of whole blood and freeze-dried plasma during global conflicts led to advancements in transfusion medicine. The transition to blood component therapy improved transfusion safety and precision. However, there is an increasing interest in using whole blood and freeze-dried plasma, supported by recent evidence suggesting potential benefits over blood component therapy, particularly in trauma cases. Canadian initiatives, such as leukoreduced whole blood production for the military, indicate efforts to address logistical challenges in delivering trauma care, especially in remote areas. Challenges remain, including logistical issues and regulatory complexities, requiring coordinated efforts for effective implementation. Overall, there's growing support for integrating whole blood and freeze-dried plasma into trauma care across Canada.<br />EARLY USE OF WHOLE BLOOD AND FREEZE-DRIED PLASMA Blood transfusions have evolved dramatically over the past 4 centuries, from the earliest experiments in the 17th century to the sophisticated transfusions [...]

Details

Language :
English
ISSN :
0008428X
Volume :
67
Issue :
5
Database :
Gale General OneFile
Journal :
Canadian Journal of Surgery
Publication Type :
Academic Journal
Accession number :
edsgcl.815088320
Full Text :
https://doi.org/10.1503/cjs.006924