A single-arm, prospective study comparing translaryngeal ultrasonography with direct visualisation by flexible laryngoscopy for vocal cord assessment in patients undergoing oesophagectomy or mediastinoscopy

Author(s): Madhavi Shetmahajan (corresponding author) [1]; M Vignesh [1,2]; Vijaya Patil [1]; Swapnil Yeshwant Parab [1]; Priya Ranganathan [1] INTRODUCTION Vocal cord (VC) palsy has been reported in up to [...]
Background and Aims: Translaryngeal ultrasonography (TLUSG) for diagnosis of vocal cord palsy, a relatively new, safe and noninvasive bedside technique with minimal risk of respiratory infection transmission, has been effective in patients with thyroid disease. We studied its use as an alternative method to visual inspection by flexible laryngoscopy (FL) for vocal cord assessment in patients undergoing thoracic surgeries. Methods: After Institutional Ethics Committee approval and trial registration, in this single-arm, prospective study, the vocal cord function of 110 patients who underwent either total oesophagectomy or mediastinoscopy was assessed immediately after extubation by both FL and TLUSG. A follow-up assessment was done by laryngoscopy using Hopkin's endoscope (HL) and a repeat TLUSG. The primary outcome was the concordance between direct visualisation (FL or HL) and TLUSG. Results: Vocal cords were successfully visualised by TLUSG in 90 of male and all female patients. Findings of FL and TLUSG done at the first assessment matched in 89 (86.4) out of 103 patients, and the degree of concordance was 0.69 (95 confidence interval [CI] =0.52-0.83). At the second assessment, HL and TLUSG findings matched in 83 (94.3) out of 88 patients, and the degree of concordance was 0.89 (95 CI = 0.77-0.98). Conclusion: TLUSG is an effective noninvasive alternative to direct visualisation for vocal cord assessment in both male and female patients undergoing thoracic surgery. Keywords: Mediastinoscopy, oesophagectomy, translaryngeal ultrasonography, ultrasonography, vocal cord assessment, vocal cord palsy, flexible laryngoscopy