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EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin
- Source :
- Cell. April 20, 2001, Vol. 105 Issue 2, p233, 12 p.
- Publication Year :
- 2001
-
Abstract
- Research has been conducted on the Eph receptors transducing repulsive short-range signals for axon guidance via actin dynamics modulation within growth cones. The cloning and characterization of the Eph receptor-interacting protein ephexin have been carried out and the results indicate the creation of the molecular link between Eph receptors and the actin cytoskeleton providing a localized regulation of the growth cone motility.
Details
- ISSN :
- 00928674
- Volume :
- 105
- Issue :
- 2
- Database :
- Gale General OneFile
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.82074374