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Effects of high glucose on insulin secretion by isolated rat islets and purified beta-cells and possible role for glycosylation
- Source :
- Diabetes. November 1989, Vol. 38 Issue 11, p1417, 6 p.
- Publication Year :
- 1989
-
Abstract
- Glucose is the major nutrient regulator for Alpha-cell insulin secretion. When Beta-cells are chronically exposed to high glucose levels, subsequent insulin secretion in response to glucose may be impaired (13). [...]
- Subjects :
- Physiological aspects
Complications and side effects
Research
Bodily secretions -- Physiological aspects -- Research
Islets of Langerhans -- Physiological aspects -- Research
Glycosylation -- Research -- Physiological aspects
Glucose -- Research -- Physiological aspects
Type 2 diabetes -- Complications and side effects -- Research
Hyperglycemia -- Physiological aspects -- Complications and side effects -- Research
Dextrose -- Research -- Physiological aspects
Islands of Langerhans -- Physiological aspects -- Research
Subjects
Details
- Language :
- English
- ISSN :
- 00121797
- Volume :
- 38
- Issue :
- 11
- Database :
- Gale General OneFile
- Journal :
- Diabetes
- Publication Type :
- Periodical
- Accession number :
- edsgcl.8246541