Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents

Authors :: Lowes, Brian D.
Gilbert, Edward M.
Abraham, William T.
Minobe, Wayne A.
Larrabee, Patti
Ferguson, Debra
Wolfel, Eugene E.
Lindenfeld, JoAnn
Tsvetkova, Tatiana
Robertson, Alastair D.
Quaiffe, Robert A.
Bristow, Michael E.
Source :: The New England Journal of Medicine. May 2, 2002, Vol. 346 Issue 18, p1357, 9 p.
Publication Year :: 2002
Abstract: Beta blockers appear to turn on genes that can reverse the adverse changes in the structure and function of heart cells in patients with dilated cardiomyopathy. This would explain why beta blockers are beneficial in these patients. Cardiomyopathy is the general term for heart disease that is not caused by coronary artery disease.

Subjects :: Cardiomyopathy, Dilated -- Drug therapy
Adrenergic beta blockers -- Physiological aspects
Gene expression

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