Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity

Authors :: Sabelle, Stephane
Renard, Pierre-Yves
Pecorella, Karine
Suzzoni-Dezard, Sophie de
Creminon, Christophe
Grassi, Jacques
Mioskowski, Charles
Source :: Journal of the American Chemical Society. May 1, 2002, Vol. 124 Issue 17, p4874, 7 p.
Publication Year :: 2002
Abstract: Research has been conducted on the acetylcholinestrase, the enzyme regulating neurotransmission. The activity of this enzyme has been investigated and the description of the 1,3-dioxetane chemiluminescent probe generated in search for a sensitive detection assay is presented.

Subjects :: Chemical research -- Analysis
Chemiluminescence -- Research
Cholinesterases -- Physiological aspects
Enzymes -- Physiological aspects
Neural transmission -- Regulation
Chemistry

Tools