Effect of magnesium ions on the tertiary structure of the hepatitis C virus IRES and its affinity for the cyclic peptide antibiotic viomycin

Authors :: Vos, Siska
Berrisford, David J.
Avis, Johanna M.
Source :: Biochemistry. April 30, 2002, Vol. 41 Issue 17, p5383, 14 p.
Publication Year :: 2002
Abstract: Research has been conducted on the ion-dependent folding unit within the hepatitis C IRES. The effect of the metal ions on the structure and stability of this region has been investigated via the use of the circular dichroism and the details are discussed.

Subjects :: Biochemistry -- Research
Magnesium -- Physiological aspects
Hepatitis C virus -- Causes of
Peptides -- Physiological aspects
Antibiotics -- Physiological aspects
Metal ions -- Physiological aspects
Circular dichroism -- Research
Biological sciences
Chemistry

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