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N(sup)4C-Alkyl-N(sup)4C cross-linked DNA: bending deformations in duplexes that contain a -CNG- interstand cross-link

Authors :
Noronha, Anne M.
Wilds, Christopher J.
Miller, Paul S.
Source :
Biochemistry. July 9, 2002, Vol. 41 Issue 27, p8605, 8 p.
Publication Year :
2002

Abstract

Results indicate that bending deformations in the helix involving the -CNG- sequence cross-linked DNA duplexes may be controlled by varying the cross-link length. Data show that the cross-link containing 2,4,or 7 methylene groups joins the C residues of a -CNG- sequence in the DnA duplex.

Details

ISSN :
00062960
Volume :
41
Issue :
27
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.89890896