Effect of homocysteine-lowering therapy with folic acid, vitamin B(sub 12), and vitamin B(sub 6) on clinical outcome after percutaneous coronary intervention: a randomized controlled trial

Vitamin B therapy may prevent the progression of coronary artery disease in patients who have had angioplasty to open up blocked coronary arteries. In many patients, the arteries become blocked again within months. In a study of 553 patients, those who took folic acid, and vitamins B6 and B12 were less likely to need a second angioplasty compared to those who took a placebo, or inactive substance.