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The ESA-NASA 'CHOICE' Study: Winterover at Concordia Station, Interior Antarctica, as an Analog for Spaceflight-Associated Immune Dysregu1ation

Authors :
Crucian, Brian E
Feuerecker, M
Salam, A. P
Rybka, A
Stowe, R. P
Morrels, M
Mehta, S. K
Quiriarte, H
Quintens, Roel
Thieme, U
Kaufmann, I
Baatout, D. S
Pierson, D. L
Sams, C. F
Chouker, A
Publication Year :
2011
Publisher :
United States: NASA Center for Aerospace Information (CASI), 2011.

Abstract

For ground-based space physiological research, the choice of analog must carefully match the system of interest. Antarctica winter-over at the European Concordia Station is potentially a ground-analog for spaceflight-associated immune dysregulation (SAID). Concordia missions consist of prolonged durations in an extreme/dangerous environment, station-based habitation, isolation, disrupted circadian rhythms and international crews. The ESA-NASA CHOICE study assess innate and adaptive immunity, viral reactivataion and stress factors during Concordia winter-over deployment. To date, not all samples have been analyzed. Here, only data will be preliminary presented for those parameters where sample/data analysis is completed (i.e., Leukocyte subsets, T cell function, and intracellular/secreted cytokine profiles.)

Subjects

Subjects :
Aerospace Medicine

Details

Language :
English
Database :
NASA Technical Reports
Notes :
BELPSO/PRODEX/ESA C90-380, , CL> 50WB0719/WB0919, , BELPSO/PRODEX/ESA C90-391
Publication Type :
Report
Accession number :
edsnas.20110008209
Document Type :
Report