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Quantification of Posterior Globe Flattening: Methodology Development and Validation

Authors :
Lumpkins, Sarah B
Garcia, Kathleen M
Sargsyan, Ashot E
Hamilton, Douglas R
Berggren, Michael D
Ebert, Douglas
Publication Year :
2012
Publisher :
United States: NASA Center for Aerospace Information (CASI), 2012.

Abstract

Microgravity exposure affects visual acuity in a subset of astronauts and mechanisms may include structural changes in the posterior globe and orbit. Particularly, posterior globe flattening has been implicated in the eyes of several astronauts. This phenomenon is known to affect some terrestrial patient populations and has been shown to be associated with intracranial hypertension. It is commonly assessed by magnetic resonance imaging (MRI), computed tomography (CT) or B-mode Ultrasound (US), without consistent objective criteria. NASA uses a semiquantitative scale of 0-3 as part of eye/orbit MRI and US analysis for occupational monitoring purposes. The goal of this study was ot initiate development of an objective quantification methodology to monitor small changes in posterior globe flattening.

Subjects

Subjects :
Aerospace Medicine

Details

Language :
English
Database :
NASA Technical Reports
Notes :
E001001
Publication Type :
Report
Accession number :
edsnas.20120007655
Document Type :
Report