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Multicenter, noncomparative study of caspofungin in combination with other antifungals as salvage therapy in adults with invasive aspergillosis.

Authors :
Maertens, J.
Glasmacher, Axel
Herbrecht, R
Thiebaut, Anne
Cordonnier, Catherine
Segal, Brahm H
Killar, John
Taylor, Arlene
Kartsonis, Nicholas
Patterson, Thomas F
Aoun, Michel
Caillot, Denis
Sable, Carole
Caspofungin Combination Therapy Study Group
Maertens, J.
Glasmacher, Axel
Herbrecht, R
Thiebaut, Anne
Cordonnier, Catherine
Segal, Brahm H
Killar, John
Taylor, Arlene
Kartsonis, Nicholas
Patterson, Thomas F
Aoun, Michel
Caillot, Denis
Sable, Carole
Caspofungin Combination Therapy Study Group
Source :
Cancer, 107 (12
Publication Year :
2006

Abstract

Caspofungin inhibits synthesis of beta-1,3-glucan, an essential component of the Aspergillus cell wall. This echinocandin has demonstrated efficacy (45% success) as salvage monotherapy of invasive aspergillosis (IA). Interest remains as to whether caspofungin, in combination with other antifungal classes, can improve the efficacy against IA.<br />Clinical Trial<br />Journal Article<br />Multicenter Study<br />Research Support, Non-U.S. Gov't<br />FLWIN<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Cancer, 107 (12
Notes :
1 full-text file(s): application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn803503148
Document Type :
Electronic Resource