A Research Program of Weight and Body Composition Management for Women with Breast Cancer

The objectives of this award are to establish a viable -program of research focusing on weight and body composition management in breast cancer, and to lay the groundwork for a feasibility study of a home-based exercise intervention for weight and body composition management. The specific aims of the award are: 1) to develop a systematic literature review of studies on exercise and breast cancer that include the outcomes of weight and/or body composition, 2) to examine the relationships between physical activity and body composition changes during adjuvant chemotherapy, and the changes in proportions of body water and lean tissue underlying changes in body composition that were suggested in the Pi's dissertation research, 3) to acquire skills in designing and applying tailored exercise programs, measuring fitness and weight-related outcomes, managing clinical trials research, and designing exercise intervention trials, and 5) to develop multidisciplinary teambuilding and grantsmanship capabilities. All tasks outlined in the Statement of Work have been addressed and all are completed or nearing completion. One manuscript has been accepted for publication thus far, and a systematic literature review has been carried out. The major differences for the original submission are in-the timeline first proposed.