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A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

Authors :
Agnandji, Selidji Todagbe
Lell, Bertrand
Fernandes, José Francisco
Abossolo, Béatrice Peggy
Methogo, Barbara Gaelle Nfono Ondo
Kabwende, Anita Lumeka
Adegnika, Ayola Akim
Mordmüller, Benjamin
Issifou, Saadou
Kremsner, Peter Gottfried
Sacarlal, Jahit
Aide, Pedro
Lanaspa, Miguel
Aponte, John J
Machevo, Sonia
Acacio, Sozinho
Bulo, Helder
Sigauque, Betuel
Macete, Eusébio
Alonso, Pedro
Abdulla, Salim
Salim, Nahya
Minja, Rose
Mpina, Maxmillian
Ahmed, Saumu
Ali, Ali Mohammed
Mtoro, Ali Takadir
Hamad, Ali Said
Mutani, Paul
Tanner, Marcel
Tinto, Halidou
D'Alessandro, Umberto
Sorgho, Hermann
Valea, Innocent
Bihoun, Biébo
Guiraud, Issa
Kaboré, Berenger
Sombié, Olivier
Guiguemdé, Robert Tinga
Ouédraogo, Jean Bosco
Hamel, Mary J
Kariuki, Simon
Oneko, Martina
Odero, Chris
Otieno, Kephas
Awino, Norbert
McMorrow, Meredith
Muturi-Kioi, Vincent
Lusingu, John
Theander, Thor G
Agnandji, Selidji Todagbe
Lell, Bertrand
Fernandes, José Francisco
Abossolo, Béatrice Peggy
Methogo, Barbara Gaelle Nfono Ondo
Kabwende, Anita Lumeka
Adegnika, Ayola Akim
Mordmüller, Benjamin
Issifou, Saadou
Kremsner, Peter Gottfried
Sacarlal, Jahit
Aide, Pedro
Lanaspa, Miguel
Aponte, John J
Machevo, Sonia
Acacio, Sozinho
Bulo, Helder
Sigauque, Betuel
Macete, Eusébio
Alonso, Pedro
Abdulla, Salim
Salim, Nahya
Minja, Rose
Mpina, Maxmillian
Ahmed, Saumu
Ali, Ali Mohammed
Mtoro, Ali Takadir
Hamad, Ali Said
Mutani, Paul
Tanner, Marcel
Tinto, Halidou
D'Alessandro, Umberto
Sorgho, Hermann
Valea, Innocent
Bihoun, Biébo
Guiraud, Issa
Kaboré, Berenger
Sombié, Olivier
Guiguemdé, Robert Tinga
Ouédraogo, Jean Bosco
Hamel, Mary J
Kariuki, Simon
Oneko, Martina
Odero, Chris
Otieno, Kephas
Awino, Norbert
McMorrow, Meredith
Muturi-Kioi, Vincent
Lusingu, John
Theander, Thor G
Source :
Agnandji , S T , Lell , B , Fernandes , J F , Abossolo , B P , Methogo , B G N O , Kabwende , A L , Adegnika , A A , Mordmüller , B , Issifou , S , Kremsner , P G , Sacarlal , J , Aide , P , Lanaspa , M , Aponte , J J , Machevo , S , Acacio , S , Bulo , H , Sigauque , B , Macete , E , Alonso , P , Abdulla , S , Salim , N , Minja , R , Mpina , M , Ahmed , S , Ali , A M , Mtoro , A T , Hamad , A S , Mutani , P , Tanner , M , Tinto , H , D'Alessandro , U , Sorgho , H , Valea , I , Bihoun , B , Guiraud , I , Kaboré , B , Sombié , O , Guiguemdé , R T , Ouédraogo , J B , Hamel , M J , Kariuki , S , Oneko , M , Odero , C , Otieno , K , Awino , N , McMorrow , M , Muturi-Kioi , V , Lusingu , J , Theander , T G & RTS,S Clinical Trials Partnership 2012 , ' A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants ' , New England Journal of Medicine , vol. 367 , no. 24 , pp. 2284-95 .
Publication Year :
2012

Abstract

The candidate malaria vaccine RTS,S/AS01 reduced episodes of both clinical and severe malaria in children 5 to 17 months of age by approximately 50% in an ongoing phase 3 trial. We studied infants 6 to 12 weeks of age recruited for the same trial.

Details

Database :
OAIster
Journal :
Agnandji , S T , Lell , B , Fernandes , J F , Abossolo , B P , Methogo , B G N O , Kabwende , A L , Adegnika , A A , Mordmüller , B , Issifou , S , Kremsner , P G , Sacarlal , J , Aide , P , Lanaspa , M , Aponte , J J , Machevo , S , Acacio , S , Bulo , H , Sigauque , B , Macete , E , Alonso , P , Abdulla , S , Salim , N , Minja , R , Mpina , M , Ahmed , S , Ali , A M , Mtoro , A T , Hamad , A S , Mutani , P , Tanner , M , Tinto , H , D'Alessandro , U , Sorgho , H , Valea , I , Bihoun , B , Guiraud , I , Kaboré , B , Sombié , O , Guiguemdé , R T , Ouédraogo , J B , Hamel , M J , Kariuki , S , Oneko , M , Odero , C , Otieno , K , Awino , N , McMorrow , M , Muturi-Kioi , V , Lusingu , J , Theander , T G & RTS,S Clinical Trials Partnership 2012 , ' A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants ' , New England Journal of Medicine , vol. 367 , no. 24 , pp. 2284-95 .
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn842768382
Document Type :
Electronic Resource