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Preterm birth, infant weight gain, and childhood asthma risk:a meta-analysis of 147,000 European children
- Source :
- Sonnenschein-van der Voort , A M M , Arends , L R , de Jongste , J C , Annesi-Maesano , I , Arshad , S H , Barros , H , Basterrechea , M , Bisgaard , H , Chatzi , L , Corpeleijn , E , Correia , S , Craig , L C , Devereux , G , Dogaru , C , Dostal , M , Duchen , K , Eggesbø , M , van der Ent , C K , Fantini , M P , Forastiere , F , Frey , U , Gehring , U , Gori , D , van der Gugten , A C , Hanke , W , Henderson , A J , Heude , B , Iñiguez , C , Inskip , H M , Keil , T , Kelleher , C C , Kogevinas , M , Kreiner-Møller , E , Kuehni , C E , Küpers , L K , Lancz , K , Larsen , P S , Lau , S , Ludvigsson , J , Mommers , M , Andersen , A-M N , Palkovicova , L , Pike , K C , Pizzi , C , Polanska , K , Porta , D , Richiardi , L , Roberts , G , Schmidt , A , Sram , R J , Sunyer , J , Thijs , C , Torrent , M , Viljoen , K , Wijga , A H , Vrijheid , M , Jaddoe , V W V & Duijts , L 2014 , ' Preterm birth, infant weight gain, and childhood asthma risk : a meta-analysis of 147,000 European children ' , The Journal of allergy and clinical immunology , vol. 133 , no. 5 , pp. 1317-29 .
- Publication Year :
- 2014
-
Abstract
- BACKGROUND: Preterm birth, low birth weight, and infant catch-up growth seem associated with an increased risk of respiratory diseases in later life, but individual studies showed conflicting results.OBJECTIVES: We performed an individual participant data meta-analysis for 147,252 children of 31 birth cohort studies to determine the associations of birth and infant growth characteristics with the risks of preschool wheezing (1-4 years) and school-age asthma (5-10 years).METHODS: First, we performed an adjusted 1-stage random-effect meta-analysis to assess the combined associations of gestational age, birth weight, and infant weight gain with childhood asthma. Second, we performed an adjusted 2-stage random-effect meta-analysis to assess the associations of preterm birth (gestational age <37 weeks) and low birth weight (<2500 g) with childhood asthma outcomes.RESULTS: Younger gestational age at birth and higher infant weight gain were independently associated with higher risks of preschool wheezing and school-age asthma (P < .05). The inverse associations of birth weight with childhood asthma were explained by gestational age at birth. Compared with term-born children with normal infant weight gain, we observed the highest risks of school-age asthma in children born preterm with high infant weight gain (odds ratio [OR], 4.47; 95% CI, 2.58-7.76). Preterm birth was positively associated with an increased risk of preschool wheezing (pooled odds ratio [pOR], 1.34; 95% CI, 1.25-1.43) and school-age asthma (pOR, 1.40; 95% CI, 1.18-1.67) independent of birth weight. Weaker effect estimates were observed for the associations of low birth weight adjusted for gestational age at birth with preschool wheezing (pOR, 1.10; 95% CI, 1.00-1.21) and school-age asthma (pOR, 1.13; 95% CI, 1.01-1.27).CONCLUSION: Younger gestational age at birth and higher infant weight gain were associated with childhood asthma outcomes. The associations of lower b
Details
- Database :
- OAIster
- Journal :
- Sonnenschein-van der Voort , A M M , Arends , L R , de Jongste , J C , Annesi-Maesano , I , Arshad , S H , Barros , H , Basterrechea , M , Bisgaard , H , Chatzi , L , Corpeleijn , E , Correia , S , Craig , L C , Devereux , G , Dogaru , C , Dostal , M , Duchen , K , Eggesbø , M , van der Ent , C K , Fantini , M P , Forastiere , F , Frey , U , Gehring , U , Gori , D , van der Gugten , A C , Hanke , W , Henderson , A J , Heude , B , Iñiguez , C , Inskip , H M , Keil , T , Kelleher , C C , Kogevinas , M , Kreiner-Møller , E , Kuehni , C E , Küpers , L K , Lancz , K , Larsen , P S , Lau , S , Ludvigsson , J , Mommers , M , Andersen , A-M N , Palkovicova , L , Pike , K C , Pizzi , C , Polanska , K , Porta , D , Richiardi , L , Roberts , G , Schmidt , A , Sram , R J , Sunyer , J , Thijs , C , Torrent , M , Viljoen , K , Wijga , A H , Vrijheid , M , Jaddoe , V W V & Duijts , L 2014 , ' Preterm birth, infant weight gain, and childhood asthma risk : a meta-analysis of 147,000 European children ' , The Journal of allergy and clinical immunology , vol. 133 , no. 5 , pp. 1317-29 .
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.ocn889825893
- Document Type :
- Electronic Resource