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Comparison of phenol red and polyethyleneglycol as nonabsorbable markers for the study of intestinal absorption in humans

Authors :
From the Department of Internal Medicine, Gastroenterology Section, University of Michigan Medical School, Ann Arbor, Mich; Clinical Research Unit, W4644 University of Michigan Hospital, 48104, Ann Arbor, Mich
From the Department of Internal Medicine, Gastroenterology Section, University of Michigan Medical School, Ann Arbor, Mich; Clinical Research Unit, W4644 University of Michigan Hospital, 48104, Ann Arbor, Mich; Royal East Sussex Hospital, Sussex, England
From the Department of Internal Medicine, Gastroenterology Section, University of Michigan Medical School, Ann Arbor, Mich; Clinical Research Unit, W4644 University of Michigan Hospital, 48104, Ann Arbor, Mich; Medical Research Council, Department of Gastroenterology, Central Middlesex Hospital, London, England
Ann Arbor
French, Arthur B.
Brown, Isabel F.
Good, Christopher J.
McLeod, Graham M.
From the Department of Internal Medicine, Gastroenterology Section, University of Michigan Medical School, Ann Arbor, Mich; Clinical Research Unit, W4644 University of Michigan Hospital, 48104, Ann Arbor, Mich
From the Department of Internal Medicine, Gastroenterology Section, University of Michigan Medical School, Ann Arbor, Mich; Clinical Research Unit, W4644 University of Michigan Hospital, 48104, Ann Arbor, Mich; Royal East Sussex Hospital, Sussex, England
From the Department of Internal Medicine, Gastroenterology Section, University of Michigan Medical School, Ann Arbor, Mich; Clinical Research Unit, W4644 University of Michigan Hospital, 48104, Ann Arbor, Mich; Medical Research Council, Department of Gastroenterology, Central Middlesex Hospital, London, England
Ann Arbor
French, Arthur B.
Brown, Isabel F.
Good, Christopher J.
McLeod, Graham M.
Publication Year :
2006

Abstract

When phenol red and polyethyleneglycol were used simultaneously as nonabsorbable markers in perfusion studies of the absorptive capacity of high jejunum in humans, apparent absorption was the same when calculated from either marker. This similar indication of dilution and of absorption by the two markers was found in normal subjects and in patients with nontropical sprue, whether aqueous or saline solutions of dextrose were infused. The similarity strengthens the evidence that either phenol red or polyethyleneglycol is a satisfactory???nonabsorbable??? marker compound to indicate dilution in perfusion studies of dextrose and electrolyte absorption in limited segments of human intestine.

Details

Database :
OAIster
Notes :
En_US
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn894072758
Document Type :
Electronic Resource