The action of enflurane (Ethrane) on cerebral blood flow

Cerebral blood flow in the grey matter was measured by the 133Xenon method in 5 patients suffering from vascular brain lesion. A first measurement was performed under N 2O fentanyl anesthesia and a second under N 2O enflurane 1% anesthesia. For both tests the subjects were maintained under stable respiratory conditions and normocapnia by artificial ventilation. Enflurane 1% caused a reduction of cerebral blood flow in all 5 patients. The decrease varied between 5 and 23%, with a mean of 12%. The decrease of cerebral blood flow under enflurane is a favorable effect for its use in neurosurgery.
SCOPUS: ar.j
info:eu-repo/semantics/published