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Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

Authors :
University of Helsinki, Department of Obstetrics and Gynecology
University of Helsinki, Institute for Molecular Medicine Finland (FIMM)
University of Helsinki, Medicum
Couch, Fergus J.
Wang, Xianshu
McGuffog, Lesley
Lee, Andrew
Olswold, Curtis
Kuchenbaecker, Karoline B.
Soucy, Penny
Fredericksen, Zachary
Barrowdale, Daniel
Dennis, Joe
Gaudet, Mia M.
Dicks, Ed
Kosel, Matthew
Healey, Sue
Sinilnikova, Olga M.
Lee, Adam
Bacot, Francois
Vincent, Daniel
Hogervorst, Frans B.L.
Peock, Susan
Stoppa-Lyonnet, Dominique
Jakubowska, Anna
Radice, Paolo
Schmutzler, Rita Katharina
Domchek, Susan M.
Piedmonte, Marion
Singer, Christian F.
Friedman, Eitan
Thomassen, Mads
Hansen, Thomas V.O.
Neuhausen, Susan L.
Szabo, Csilla I.
Blanco, Ignacio
Greene, Mark H.
Karlan, Beth Y.
Garber, Judy
Phelan, Catherine M.
Weitzel, Jeffrey N.
Montagna, Marco
Olah, Edith
Andrulis, Irene L.
Godwin, Andrew K.
Yannoukakos, Drakoulis
Goldgar, David E.
Caldes, Trinidad
Nevanlinna, Heli
Osorio, Ana
Terry, Mary Beth
Daly, Mary B.
Van Rensburg, Elizabeth J.
Hamann, Ute
Ramus, Susan J.
Toland, Amanda Ewart
Caligo, Maria A.
Olopade, Olufunmilayo I.
Tung, Nadine
Claes, Kathleen
Beattie, Mary S.
Southey, Melissa C.
Imyanitov, Evgeny N.
Tischkowitz, Marc
Janavicius, Ramunas
John, Esther M.
Kwong, Ava
Diez, Orland
Balmana, Judith
Barkardottir, Rosa B.
Arun, Banu K.
Rennert, Gad
Teo, Soo-Hwang
Ganz, Patricia A.
Campbell, Ian
Van der Hout, Annemarie H.
Van Deurzen, Carolien H.M.
Seynaeve, Caroline
Garcia, Encarna B. Gomez
Van Leeuwen, Flora E.
Meijers-Heijboer, Hanne E.J.
Gille, Johannes J.P.
Ausems, Margreet G.E.M.
Blok, Marinus J.
Ligtenberg, Marjolijn J.L.
Rookus, Matti A.
Devilee, Peter
Verhoef, Senno
Van Os, Theo A.M.
Wijnen, Juul T.
Frost, Debra
Ellis, Steve
Fineberg, Elena
Platte, Radka
Evans, D. Gareth
Izatt, Louise
Eeles, Rosalind A.
Adlard, Julian
Eccles, Diana M.
Cook, Jackie
Brewer, Carole
Douglas, Fiona
Hodgson, Shirley
Morrison, Patrick J.
Side, Lucy E.
Donaldson, Alan
Houghton, Catherine
Rogers, Mark T.
Dorkins, Huw
Eason, Jacqueline
Gregory, Helen
McCann, Emma
Murray, Alex
Calender, Alain
Hardouin, Agnes
Berthet, Pascaline
Delnatte, Capucine
Nogues, Catherine
Lasset, Christine
Houdayer, Claude
Leroux, Dominique
Rouleau, Etienne
Prieur, Fabienne
Damiola, Francesca
Sobol, Hagay
Coupier, Isabelle
Venat-Bouvet, Laurence
Castera, Laurent
Gauthier-Villars, Marion
Leone, Melanie
Pujol, Pascal
Mazoyer, Sylvie
Bignon, Yves-Jean
Zlowocka-Perlowska, Elzbieta
Gronwald, Jacek
Lubinski, Jan
Durda, Katarzyna
Jaworska, Katarzyna
Huzarski, Tomasz
Spurdle, Amanda B.
Viel, Alessandra
Peissel, Bernard
Bonanni, Bernardo
Melloni, Giulia
Ottini, Laura
Papi, Laura
Varesco, Liliana
Tibiletti, Maria Grazia
Peterlongo, Paolo
Volorio, Sara
Manoukian, Siranoush
Pensotti, Valeria
Arnold, Norbert
Engel, Christoph
Deissler, Helmut
Gadzicki, Dorothea
Gehrig, Andrea
Kast, Karin
Rhiem, Kerstin
Meindl, Alfons
Niederacher, Dieter
Ditsch, Nina
Plendl, Hansjoerg
Preisler-Adams, Sabine
Engert, Stefanie
Sutter, Christian
Varon-Mateeva, Raymonda
Wappenschmidt, Barbara
Weber, Bernhard H.F.
Arver, Brita
Stenmark-Askmalm, Marie
Loman, Niklas
Rosenquist, Richard
Einbeigi, Zakaria
Nathanson, Katherine L.
Rebbeck, Timothy R.
Blank, Stephanie V.
Cohn, David E.
Rodriguez, Gustavo C.
Small, Laurie
Friedlander, Michael
Bae-Jump, Victoria L.
Fink-Retter, Anneliese
Rappaport, Christine
Gschwantler-Kaulich, Daphne
Pfeiler, Georg
Tea, Muy-Kheng
Lindor, Noralane M.
Kaufman, Bella
Paluch, Shani Shimon
Laitman, Yael
Skytte, Anne-Bine
Gerdes, Anne-Marie
Pedersen, Inge Sokilde
Moeller, Sanne Traasdahl
Kruse, Torben A.
Jensen, Uffe Birk
Vijai, Joseph
Sarrel, Kara
Robson, Mark
Kauff, Noah
Mulligan, Anna Marie
Glendon, Gord
Ozcelik, Hilmi
Ejlertsen, Bent
Nielsen, Finn C.
Jonson, Lars
Andersen, Mette K.
Ding, Yuan Chun
Steele, Linda
Foretova, Lenka
Teule, Alex
Lazaro, Conxi
Brunet, Joan
Angel Pujana, Miquel
Mai, Phuong L.
Loud, Jennifer T.
Walsh, Christine
Lester, Jenny
Orsulic, Sandra
Narod, Steven A.
Herzog, Josef
Sand, Sharon R.
Tognazzo, Silvia
Agata, Simona
Vaszko, Tibor
Weaver, Joellen
Stavropoulou, Alexandra V.
Buys, Saundra S.
Romero, Atocha
De la Hoya, Miguel
Aittomäki, Kristiina
Muranen, Taru A.
Duran, Mercedes
Chung, Wendy K.
Lasa, Adriana
Dorfling, Cecilia M.
Miron, Alexander
Benitez, Javier
Senter, Leigha
Huo, Dezheng
Chan, Salina B.
Sokolenko, Anna P.
Chiquette, Jocelyne
Tihomirova, Laima
Friebel, Tara M.
Agnarsson, Bjarni A.
Lu, Karen H.
Lejbkowicz, Flavio
James, Paul A.
Hall, Per
Dunning, Alison M.
Tessier, Daniel
Cunningham, Julie
Slager, Susan L.
Wang, Chen
Hart, Steven
Stevens, Kristen
Simard, Jacques
Pastinen, Tomi
Pankratz, Vernon S.
Offit, Kenneth
Easton, Douglas F.
Chenevix-Trench, Georgia
Antoniou, Antonis C.
KConFab Investigators
SWE-BRCA
Ontario Canc Genetics Network
HEBON
EMBRACE
GEMO Study Collaborators
BCFR
CIMBA
University of Helsinki, Department of Obstetrics and Gynecology
University of Helsinki, Institute for Molecular Medicine Finland (FIMM)
University of Helsinki, Medicum
Couch, Fergus J.
Wang, Xianshu
McGuffog, Lesley
Lee, Andrew
Olswold, Curtis
Kuchenbaecker, Karoline B.
Soucy, Penny
Fredericksen, Zachary
Barrowdale, Daniel
Dennis, Joe
Gaudet, Mia M.
Dicks, Ed
Kosel, Matthew
Healey, Sue
Sinilnikova, Olga M.
Lee, Adam
Bacot, Francois
Vincent, Daniel
Hogervorst, Frans B.L.
Peock, Susan
Stoppa-Lyonnet, Dominique
Jakubowska, Anna
Radice, Paolo
Schmutzler, Rita Katharina
Domchek, Susan M.
Piedmonte, Marion
Singer, Christian F.
Friedman, Eitan
Thomassen, Mads
Hansen, Thomas V.O.
Neuhausen, Susan L.
Szabo, Csilla I.
Blanco, Ignacio
Greene, Mark H.
Karlan, Beth Y.
Garber, Judy
Phelan, Catherine M.
Weitzel, Jeffrey N.
Montagna, Marco
Olah, Edith
Andrulis, Irene L.
Godwin, Andrew K.
Yannoukakos, Drakoulis
Goldgar, David E.
Caldes, Trinidad
Nevanlinna, Heli
Osorio, Ana
Terry, Mary Beth
Daly, Mary B.
Van Rensburg, Elizabeth J.
Hamann, Ute
Ramus, Susan J.
Toland, Amanda Ewart
Caligo, Maria A.
Olopade, Olufunmilayo I.
Tung, Nadine
Claes, Kathleen
Beattie, Mary S.
Southey, Melissa C.
Imyanitov, Evgeny N.
Tischkowitz, Marc
Janavicius, Ramunas
John, Esther M.
Kwong, Ava
Diez, Orland
Balmana, Judith
Barkardottir, Rosa B.
Arun, Banu K.
Rennert, Gad
Teo, Soo-Hwang
Ganz, Patricia A.
Campbell, Ian
Van der Hout, Annemarie H.
Van Deurzen, Carolien H.M.
Seynaeve, Caroline
Garcia, Encarna B. Gomez
Van Leeuwen, Flora E.
Meijers-Heijboer, Hanne E.J.
Gille, Johannes J.P.
Ausems, Margreet G.E.M.
Blok, Marinus J.
Ligtenberg, Marjolijn J.L.
Rookus, Matti A.
Devilee, Peter
Verhoef, Senno
Van Os, Theo A.M.
Wijnen, Juul T.
Frost, Debra
Ellis, Steve
Fineberg, Elena
Platte, Radka
Evans, D. Gareth
Izatt, Louise
Eeles, Rosalind A.
Adlard, Julian
Eccles, Diana M.
Cook, Jackie
Brewer, Carole
Douglas, Fiona
Hodgson, Shirley
Morrison, Patrick J.
Side, Lucy E.
Donaldson, Alan
Houghton, Catherine
Rogers, Mark T.
Dorkins, Huw
Eason, Jacqueline
Gregory, Helen
McCann, Emma
Murray, Alex
Calender, Alain
Hardouin, Agnes
Berthet, Pascaline
Delnatte, Capucine
Nogues, Catherine
Lasset, Christine
Houdayer, Claude
Leroux, Dominique
Rouleau, Etienne
Prieur, Fabienne
Damiola, Francesca
Sobol, Hagay
Coupier, Isabelle
Venat-Bouvet, Laurence
Castera, Laurent
Gauthier-Villars, Marion
Leone, Melanie
Pujol, Pascal
Mazoyer, Sylvie
Bignon, Yves-Jean
Zlowocka-Perlowska, Elzbieta
Gronwald, Jacek
Lubinski, Jan
Durda, Katarzyna
Jaworska, Katarzyna
Huzarski, Tomasz
Spurdle, Amanda B.
Viel, Alessandra
Peissel, Bernard
Bonanni, Bernardo
Melloni, Giulia
Ottini, Laura
Papi, Laura
Varesco, Liliana
Tibiletti, Maria Grazia
Peterlongo, Paolo
Volorio, Sara
Manoukian, Siranoush
Pensotti, Valeria
Arnold, Norbert
Engel, Christoph
Deissler, Helmut
Gadzicki, Dorothea
Gehrig, Andrea
Kast, Karin
Rhiem, Kerstin
Meindl, Alfons
Niederacher, Dieter
Ditsch, Nina
Plendl, Hansjoerg
Preisler-Adams, Sabine
Engert, Stefanie
Sutter, Christian
Varon-Mateeva, Raymonda
Wappenschmidt, Barbara
Weber, Bernhard H.F.
Arver, Brita
Stenmark-Askmalm, Marie
Loman, Niklas
Rosenquist, Richard
Einbeigi, Zakaria
Nathanson, Katherine L.
Rebbeck, Timothy R.
Blank, Stephanie V.
Cohn, David E.
Rodriguez, Gustavo C.
Small, Laurie
Friedlander, Michael
Bae-Jump, Victoria L.
Fink-Retter, Anneliese
Rappaport, Christine
Gschwantler-Kaulich, Daphne
Pfeiler, Georg
Tea, Muy-Kheng
Lindor, Noralane M.
Kaufman, Bella
Paluch, Shani Shimon
Laitman, Yael
Skytte, Anne-Bine
Gerdes, Anne-Marie
Pedersen, Inge Sokilde
Moeller, Sanne Traasdahl
Kruse, Torben A.
Jensen, Uffe Birk
Vijai, Joseph
Sarrel, Kara
Robson, Mark
Kauff, Noah
Mulligan, Anna Marie
Glendon, Gord
Ozcelik, Hilmi
Ejlertsen, Bent
Nielsen, Finn C.
Jonson, Lars
Andersen, Mette K.
Ding, Yuan Chun
Steele, Linda
Foretova, Lenka
Teule, Alex
Lazaro, Conxi
Brunet, Joan
Angel Pujana, Miquel
Mai, Phuong L.
Loud, Jennifer T.
Walsh, Christine
Lester, Jenny
Orsulic, Sandra
Narod, Steven A.
Herzog, Josef
Sand, Sharon R.
Tognazzo, Silvia
Agata, Simona
Vaszko, Tibor
Weaver, Joellen
Stavropoulou, Alexandra V.
Buys, Saundra S.
Romero, Atocha
De la Hoya, Miguel
Aittomäki, Kristiina
Muranen, Taru A.
Duran, Mercedes
Chung, Wendy K.
Lasa, Adriana
Dorfling, Cecilia M.
Miron, Alexander
Benitez, Javier
Senter, Leigha
Huo, Dezheng
Chan, Salina B.
Sokolenko, Anna P.
Chiquette, Jocelyne
Tihomirova, Laima
Friebel, Tara M.
Agnarsson, Bjarni A.
Lu, Karen H.
Lejbkowicz, Flavio
James, Paul A.
Hall, Per
Dunning, Alison M.
Tessier, Daniel
Cunningham, Julie
Slager, Susan L.
Wang, Chen
Hart, Steven
Stevens, Kristen
Simard, Jacques
Pastinen, Tomi
Pankratz, Vernon S.
Offit, Kenneth
Easton, Douglas F.
Chenevix-Trench, Georgia
Antoniou, Antonis C.
KConFab Investigators
SWE-BRCA
Ontario Canc Genetics Network
HEBON
EMBRACE
GEMO Study Collaborators
BCFR
CIMBA
Source :
Couch, F J, Wang, X, McGuffog, L, Lee, A, Olswold, C, Kuchenbaecker, K B, Soucy, P, Fredericksen, Z, Barrowdale, D, Dennis, J, Gaudet, M M, Dicks, E, Kosel, M, Healey, S, Sinilnikova, O M, Lee, A, Bacot, F, Vincent, D, Hogervorst, F B L, Peock, S, Stoppa-Lyonnet, D, Jakubowska, A, Radice, P, Schmutzler, R K, Domchek, S M, Piedmonte, M, Singer, C F, Friedman, E, Thomassen, M, Hansen, T V O, Neuhausen, S L, Szabo, C I, Blanco, I, Greene, M H, Karlan, B Y, Garber, J, Phelan, C M, Weitzel, J N, Montagna, M, Olah, E, Andrulis, I L, Godwin, A K, Yannoukakos, D, Goldgar, D E, Caldes, T, Nevanlinna, H, Osorio, A, Terry, M B, Daly, M B, van Rensburg, E J, Hamann, U, Ramus, S J, Toland, A E, Caligo, M A, Olopade, O I, Tung, N, Claes, K, Beattie, M S, Southey, M C, Imyanitov, E N, Tischkowitz, M, Janavicius, R, John, E M, Kwong, A, Diez, O, Balmana, J, Barkardottir, R B, Arun, B K, Rennert, G, Teo, S-H, Ganz, P A, Campbell, I, van der Hout, A H, van Deurzen, C H M, Seynaeve, C, Garcia, E B G, van Leeuwen, F E, Meijers-Heijboer, H E J, Gille, J J P, Ausems, M G E M, Blok, M J, Ligtenberg, M J L, Rookus, M A, Devilee, P, Verhoef, S, van Os, T A M, Wijnen, J T, Frost, D, Ellis, S, Fineberg, E, Platte, R, Evans, D G, Izatt, L, Eeles, R A, Adlard, J, Eccles, D M, Cook, J, Brewer, C, Douglas, F, Hodgson, S, Morrison, P J, Side, L E, Donaldson, A, Houghton, C, Rogers, M T, Dorkins, H, Eason, J, Gregory, H, McCann, E, Murray, A, Calender, A, Hardouin, A, Berthet, P, Delnatte, C, Nogues, C, Lasset, C, Houdayer, C, Leroux, D, Rouleau, E, Prieur, F, Damiola, F, Sobol, H, Coupier, I, Venat-Bouvet, L, Castera, L, Gauthier-Villars, M, Leone, M, Pujol, P, Mazoyer, S, Bignon, Y-J, Zlowocka-Perlowska, E, Gronwald, J, Lubinski, J, Du
Publication Year :
2013

Details

Database :
OAIster
Journal :
Couch, F J, Wang, X, McGuffog, L, Lee, A, Olswold, C, Kuchenbaecker, K B, Soucy, P, Fredericksen, Z, Barrowdale, D, Dennis, J, Gaudet, M M, Dicks, E, Kosel, M, Healey, S, Sinilnikova, O M, Lee, A, Bacot, F, Vincent, D, Hogervorst, F B L, Peock, S, Stoppa-Lyonnet, D, Jakubowska, A, Radice, P, Schmutzler, R K, Domchek, S M, Piedmonte, M, Singer, C F, Friedman, E, Thomassen, M, Hansen, T V O, Neuhausen, S L, Szabo, C I, Blanco, I, Greene, M H, Karlan, B Y, Garber, J, Phelan, C M, Weitzel, J N, Montagna, M, Olah, E, Andrulis, I L, Godwin, A K, Yannoukakos, D, Goldgar, D E, Caldes, T, Nevanlinna, H, Osorio, A, Terry, M B, Daly, M B, van Rensburg, E J, Hamann, U, Ramus, S J, Toland, A E, Caligo, M A, Olopade, O I, Tung, N, Claes, K, Beattie, M S, Southey, M C, Imyanitov, E N, Tischkowitz, M, Janavicius, R, John, E M, Kwong, A, Diez, O, Balmana, J, Barkardottir, R B, Arun, B K, Rennert, G, Teo, S-H, Ganz, P A, Campbell, I, van der Hout, A H, van Deurzen, C H M, Seynaeve, C, Garcia, E B G, van Leeuwen, F E, Meijers-Heijboer, H E J, Gille, J J P, Ausems, M G E M, Blok, M J, Ligtenberg, M J L, Rookus, M A, Devilee, P, Verhoef, S, van Os, T A M, Wijnen, J T, Frost, D, Ellis, S, Fineberg, E, Platte, R, Evans, D G, Izatt, L, Eeles, R A, Adlard, J, Eccles, D M, Cook, J, Brewer, C, Douglas, F, Hodgson, S, Morrison, P J, Side, L E, Donaldson, A, Houghton, C, Rogers, M T, Dorkins, H, Eason, J, Gregory, H, McCann, E, Murray, A, Calender, A, Hardouin, A, Berthet, P, Delnatte, C, Nogues, C, Lasset, C, Houdayer, C, Leroux, D, Rouleau, E, Prieur, F, Damiola, F, Sobol, H, Coupier, I, Venat-Bouvet, L, Castera, L, Gauthier-Villars, M, Leone, M, Pujol, P, Mazoyer, S, Bignon, Y-J, Zlowocka-Perlowska, E, Gronwald, J, Lubinski, J, Du
Notes :
21, Couch, F J, Wang, X, McGuffog, L, Lee, A, Olswold, C, Kuchenbaecker, K B, Soucy, P, Fredericksen, Z, Barrowdale, D, Dennis, J, Gaudet, M M, Dicks, E, Kosel, M, Healey, S, Sinilnikova, O M, Lee, A, Bacot, F, Vincent, D, Hogervorst, F B L, Peock, S, Stoppa-Lyonnet, D, Jakubowska, A, Radice, P, Schmutzler, R K, Domchek, S M, Piedmonte, M, Singer, C F, Friedman, E, Thomassen, M, Hansen, T V O, Neuhausen, S L, Szabo, C I, Blanco, I, Greene, M H, Karlan, B Y, Garber, J, Phelan, C M, Weitzel, J N, Montagna, M, Olah, E, Andrulis, I L, Godwin, A K, Yannoukakos, D, Goldgar, D E, Caldes, T, Nevanlinna, H, Osorio, A, Terry, M B, Daly, M B, van Rensburg, E J, Hamann, U, Ramus, S J, Toland, A E, Caligo, M A, Olopade, O I, Tung, N, Claes, K, Beattie, M S, Southey, M C, Imyanitov, E N, Tischkowitz, M, Janavicius, R, John, E M, Kwong, A, Diez, O, Balmana, J, Barkardottir, R B, Arun, B K, Rennert, G, Teo, S-H, Ganz, P A, Campbell, I, van der Hout, A H, van Deurzen, C H M, Seynaeve, C, Garcia, E B G, van Leeuwen, F E, Meijers-Heijboer, H E J, Gille, J J P, Ausems, M G E M, Blok, M J, Ligtenberg, M J L, Rookus, M A, Devilee, P, Verhoef, S, van Os, T A M, Wijnen, J T, Frost, D, Ellis, S, Fineberg, E, Platte, R, Evans, D G, Izatt, L, Eeles, R A, Adlard, J, Eccles, D M, Cook, J, Brewer, C, Douglas, F, Hodgson, S, Morrison, P J, Side, L E, Donaldson, A, Houghton, C, Rogers, M T, Dorkins, H, Eason, J, Gregory, H, McCann, E, Murray, A, Calender, A, Hardouin, A, Berthet, P, Delnatte, C, Nogues, C, Lasset, C, Houdayer, C, Leroux, D, Rouleau, E, Prieur, F, Damiola, F, Sobol, H, Coupier, I, Venat-Bouvet, L, Castera, L, Gauthier-Villars, M, Leone, M, Pujol, P, Mazoyer, S, Bignon, Y-J, Zlowocka-Perlowska, E, Gronwald, J, Lubinski, J, Du, English
Accession number :
edsoai.ocn951544890