Lactobacillus plantarum WCFS1 and its host interaction

Authors :: University of Helsinki, Medicum
van den Nieuwboer, Maurits
van Hemert, Saskia
Claassen, Eric
de Vos, Willem M.
University of Helsinki, Medicum
van den Nieuwboer, Maurits
van Hemert, Saskia
Claassen, Eric
de Vos, Willem M.
Source :: van den Nieuwboer , M , van Hemert , S , Claassen , E & de Vos , W M 2016 , ' Lactobacillus plantarum WCFS1 and its host interaction : a dozen years after the genome ' Microbial Biotechnology , vol 9 , no. 4 , pp. 452-465 . DOI: 10.1111/1751-7915.12368
Publication Year :: 2016
Abstract: Lactobacillus plantarum WCFS1 is one of the best studied Lactobacilli, notably as its genome was unravelled over 12years ago. L.plantarum WCFS1 can be grown to high densities, is amenable to genetic transformation and highly robust with a relatively high survival rate during the gastrointestinal passage. In this review, we present and discuss the main insights provided by the functional genomics research on L.plantarum WCFS1 with specific attention for the molecular mechanisms related to its interaction with the human host and its potential to modify the immune system, and induce other health-related benefits. Whereas most insight has been gained in mouse and other model studies, onlyfive human studies have been reported with L.plantarum WCFS1. Hence NCIMB 8826 (the parental strain of L.plantarum WCFS1) in human trials as to capitalize on the wealth of knowledge that is summarized here.

Database :: OAIster
Journal :: van den Nieuwboer , M , van Hemert , S , Claassen , E & de Vos , W M 2016 , ' Lactobacillus plantarum WCFS1 and its host interaction : a dozen years after the genome ' Microbial Biotechnology , vol 9 , no. 4 , pp. 452-465 . DOI: 10.1111/1751-7915.12368
Notes :: 14, English
Publication Type :: Electronic Resource
Accession number :: edsoai.ocn956348543
Document Type :: Electronic Resource