First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)-a systematic review and individual patient data meta-analysis

Authors :: Kasenda, B. (Benjamin)
Ferreri, A.J.M. (Andrés J.M.)
Marturano, E.
Forst, D.
Bromberg, J.E.C. (Jacoline)
Ghesquieres, H.
Ferlay, C.
Blay, J.Y. (Jean Yves)
Hoang-Xuan, K. (Khê)
Pulczynski, E.J.
Fosså, A.
Okoshi, Y.
Chiba, S. (Shigeru)
Fritsch, K. (Kristina)
Omuro, A.
O'Neill, B.P.
Bairey, O.
Schandelmaier, S.
Gloy, V.
Bhatnagar, N.
Haug, S.
Rahner, S.
Batchelor, T.T. (Tracy)
Illerhaus, G. (Gerald)
Brie, M.
Kasenda, B. (Benjamin)
Ferreri, A.J.M. (Andrés J.M.)
Marturano, E.
Forst, D.
Bromberg, J.E.C. (Jacoline)
Ghesquieres, H.
Ferlay, C.
Blay, J.Y. (Jean Yves)
Hoang-Xuan, K. (Khê)
Pulczynski, E.J.
Fosså, A.
Okoshi, Y.
Chiba, S. (Shigeru)
Fritsch, K. (Kristina)
Omuro, A.
O'Neill, B.P.
Bairey, O.
Schandelmaier, S.
Gloy, V.
Bhatnagar, N.
Haug, S.
Rahner, S.
Batchelor, T.T. (Tracy)
Illerhaus, G. (Gerald)
Brie, M.
Publication Year :: 2015
Abstract: Background: To investigate prognosis and effects of first-line therapy in elderly primary central nervous system lymphoma (PCNSL) patients. Patients and methods: A systematic review of studies about first-line therapy in immunocompetent patients ≥60 years with PCNSL until 2014 and a meta-analysis of individual patient data from eligible studies and international collaborators were carried out. Results: We identified 20 eligible studies; from 13

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