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Controlled Clinical Trial of L-Dopa and Nafoxidine in Advanced breast Cancer: An E.O.R.T.C. Study

Authors :
Heuson, Jean-Claude
Blonk-Van Der Wijst, J.
Drochmans, Alfons
Maass, Heinrich
Cheix, Françoise
Sobrinho, Luís Gonçalves
Nowakowski, H.
Heuson, Jean-Claude
Blonk-Van Der Wijst, J.
Drochmans, Alfons
Maass, Heinrich
Cheix, Françoise
Sobrinho, Luís Gonçalves
Nowakowski, H.
Source :
British medical journal, 2 (5973
Publication Year :
1975

Abstract

L-Dopa lowers plasma prolactin levels, and there have been reports that patients with advanced breast cancer have been successfully treated with L-dopa. To test the potential value of L-dopa in this disease a randomized clinical trial of L-dopa and nafoxidine (as the reference compound) was conducted in postmenopausal women with advanced breast cancer. Objective remissions were obtained in seven out of 36 patients (19%) treated with nafoxidine but in none out of 40 patients treated with L-dopa. L-Dopa in the dose schedule used seems to be ineffective in advanced breast cancer. © 1975, British Medical Journal Publishing Group. All rights reserved.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
British medical journal, 2 (5973
Notes :
1 full-text file(s): application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.ocn961114020
Document Type :
Electronic Resource