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An AIE-based Bioprobe for Differentiating the Early and Late Stages of Apoptosis Mediated by H2O2

Authors :
Leung, Chun Sing CHEM
Zhao, Engui
Kwok, Tsz Kin
Lam, Wing Yip
Leung, Wai Tung
Deng, Haiqin
Tang, Benzhong
Leung, Chun Sing CHEM
Zhao, Engui
Kwok, Tsz Kin
Lam, Wing Yip
Leung, Wai Tung
Deng, Haiqin
Tang, Benzhong
Publication Year :
2016

Abstract

A bioprobe, TPE–Zn2BDPA, with aggregation-induced emission characteristics was designed and synthesized to differentiate the early and late stages of apoptosis mediated by H2O2. TPE–Zn2BDPA does not respond to healthy cells, but it selectively lights up the membrane of apopotic cells in both stages with brighter fluorescence in the late apoptotic stage.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1020853153
Document Type :
Electronic Resource