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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Authors :
Teumer, A. (Alexander) Qi, Q. Nethander, M. (Maria) Aschard, H. (Hugues) Bandinelli, S. (Stefania) Beekman, M. (Marian) Berndt, S.I. (Sonja) Bidlingmaier, M. (Martin) Broer, L. (Linda) Cappola, A.R. (Anne) Ceda, G.P. (Gian Paolo) Chanock, S.J. (Stephen) Chen, M.-H. (Ming-Huei) Chen, T.C. (Tai C.) Chen, Y.D. (Y.) Chung, J. (Jonathan) Del Greco Miglianico, F. (Fabiola) Eriksson, J. (Joel) Ferrucci, L. (Luigi) Friedrich, N. (Nele) Gnewuch, C. (Carsten) Goodarzi, M. (Mark) Grarup, N. (Niels) Guo, T. (Tingwei) Hammer, E. (Elke) Hayes, R.B. (Richard) Hicks, A.A. (Andrew) Hofman, A. (Albert) Houwing-Duistermaat, J.J. (Jeanine) Hu, F. (Frank) Hunter, D. (David) Husemoen, L.L.N. (Lise Lotte) Isaacs, A.J. (Aaron) Jacobs, K.B. (Kevin) Janssen, J.A.M.J.L. (Joop) Jansson, J.-O. (John-Olov) Jehmlich, N. (Nico) Johnson, S. (Simon) Juul, A. (Anders) Karlsson, M. (Magnus) Kilpeläinen, T.O. (Tuomas) Kovacs, P. (Peter) Kraft, P. (Peter) Li, C. (Chao) Linneberg, A. (Allan) Liu, Y. (YongMei) Loos, R.J.F. (Ruth) Lorentzon, M. (Mattias) Lu, Y. (Yingchang) Maggio, M. (Marcello) Mägi, R. (Reedik) Meigs, J.B. (James) Mellström, D. (Dan) Nauck, M. (Matthias) Newman, A.B. (Anne B.) Pollak, M.N. (Michael) Pramstaller, P.P. (Peter Paul) Prokopenko, I. (Inga) Psaty, B.M. (Bruce) Reincke, M. (Martin) Rimm, E.B. (Eric B.) Rotter, J.I. (Jerome I.) Saint Pierre, A. (Aude) Schurmann, C. (Claudia) Seshadri, S. (Sudha) Sjögren, K. (Klara) Slagboom, P.E. (Eline) Strickler, H.D. (Howard D.) Stumvoll, M. (Michael) Suh, Y. (Yousin) Sun, Q. (Qi) Zhang, C. (Cuilin) Svensson, J. (Johan) Tanaka, T. (Toshiko) Tare, A. (Archana) Tönjes, A. (Anke) Uh, H.-W. (Hae-Won) Duijn, C.M. (Cornelia) van Heemst, D. (Diana) van Vandenput, L. (Liesbeth) Vasan, R.S. (Ramachandran Srini) Völker, U. (Uwe) Willems, S.M. (Sara) Ohlsson, C. (Claes) Wallaschofski, H. (Henri) Kaplan, R.C. (Robert) Teumer, A. (Alexander) Qi, Q. Nethander, M. (Maria) Aschard, H. (Hugues) Bandinelli, S. (Stefania) Beekman, M. (Marian) Berndt, S.I. (Sonja) Bidlingmaier, M. (Martin) Broer, L. (Linda) Cappola, A.R. (Anne) Ceda, G.P. (Gian Paolo) Chanock, S.J. (Stephen) Chen, M.-H. (Ming-Huei) Chen, T.C. (Tai C.) Chen, Y.D. (Y.) Chung, J. (Jonathan) Del Greco Miglianico, F. (Fabiola) Eriksson, J. (Joel) Ferrucci, L. (Luigi) Friedrich, N. (Nele) Gnewuch, C. (Carsten) Goodarzi, M. (Mark) Grarup, N. (Niels) Guo, T. (Tingwei) Hammer, E. (Elke) Hayes, R.B. (Richard) Hicks, A.A. (Andrew) Hofman, A. (Albert) Houwing-Duistermaat, J.J. (Jeanine) Hu, F. (Frank) Hunter, D. (David) Husemoen, L.L.N. (Lise Lotte) Isaacs, A.J. (Aaron) Jacobs, K.B. (Kevin) Janssen, J.A.M.J.L. (Joop) Jansson, J.-O. (John-Olov) Jehmlich, N. (Nico) Johnson, S. (Simon) Juul, A. (Anders) Karlsson, M. (Magnus) Kilpeläinen, T.O. (Tuomas) Kovacs, P. (Peter) Kraft, P. (Peter) Li, C. (Chao) Linneberg, A. (Allan) Liu, Y. (YongMei) Loos, R.J.F. (Ruth) Lorentzon, M. (Mattias) Lu, Y. (Yingchang) Maggio, M. (Marcello) Mägi, R. (Reedik) Meigs, J.B. (James) Mellström, D. (Dan) Nauck, M. (Matthias) Newman, A.B. (Anne B.) Pollak, M.N. (Michael) Pramstaller, P.P. (Peter Paul) Prokopenko, I. (Inga) Psaty, B.M. (Bruce) Reincke, M. (Martin) Rimm, E.B. (Eric B.) Rotter, J.I. (Jerome I.) Saint Pierre, A. (Aude) Schurmann, C. (Claudia) Seshadri, S. (Sudha) Sjögren, K. (Klara) Slagboom, P.E. (Eline) Strickler, H.D. (Howard D.) Stumvoll, M. (Michael) Suh, Y. (Yousin) Sun, Q. (Qi) Zhang, C. (Cuilin) Svensson, J. (Johan) Tanaka, T. (Toshiko) Tare, A. (Archana) Tönjes, A. (Anke) Uh, H.-W. (Hae-Won) Duijn, C.M. (Cornelia) van Heemst, D. (Diana) van Vandenput, L. (Liesbeth) Vasan, R.S. (Ramachandran Srini) Völker, U. (Uwe) Willems, S.M. (Sara) Ohlsson, C. (Claes) Wallaschofski, H. (Henri) Kaplan, R.C. (Robert)
Publication Year :
2016
Abstract
The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases including cardiovascular diseases, diabetes, and cancer. Through
Details
Database :
OAIster
Notes :
application/pdf, Aging Cell vol. 15 no. 5, pp. 811-824, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1022217406
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1111.acel.12490