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Attenuation of Experimental Atherosclerosis by Interleukin-19.
- Source :
- Arteriosclerosis, Thrombosis and Vascular Biology; 33(10), pp 2316-2324 (2013); ISSN: 1524-4636
- Publication Year :
- 2013
-
Abstract
- Interleukin-19 (IL-19) is a putative Th2, anti-inflammatory interleukin. Its expression and potential role in atherogenesis are unknown. IL-19 is not detected in normal artery and is expressed to a greater degree in plaque from symptomatic versus asymptomatic patients, suggesting a compensatory counter-regulatory function. We tested whether IL-19 could reduce atherosclerosis in susceptible mice and identified plausible mechanisms.
Details
- Database :
- OAIster
- Journal :
- Arteriosclerosis, Thrombosis and Vascular Biology; 33(10), pp 2316-2324 (2013); ISSN: 1524-4636
- Notes :
- application/pdf, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1023427045
- Document Type :
- Electronic Resource