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SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8- BROMO-2’-DEOXYGUANOSINE
- Publication Year :
- 2001
-
Abstract
- The preparation of oligonucleotides containing 8-bromo-2′-deoxyguanosine is described. Substitution of G by 8-bromoguanine on an alternating CG decamer stabilizes the Z-form in such a way that the B-form was not observed. Melting temperatures showed that duplexes in which 8-bromo-2′-deoxyguanosine paired with natural bases were much less stable.
Details
- Database :
- OAIster
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1104776457
- Document Type :
- Electronic Resource