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Impact of IL-18 on inflammation

Authors :
Tripodi, Domenico
Macauro, G
Anogeianaki, A
Castellani, M. L.
Pandolfi, Franco
Felaco, P
Toniato, E
De Lutiis, M. A.
Fulcheri, M.
Tete, S.
Galzio, R.
Salini, V.
Caraffa, A.
Antinolfi, P.
Frydas, I.
Sabatino, G.
Shaik Dasthagirisaheb, Y. B.
Pandolfi, Franco (ORCID:0000-0001-8799-8173)
Tripodi, Domenico
Macauro, G
Anogeianaki, A
Castellani, M. L.
Pandolfi, Franco
Felaco, P
Toniato, E
De Lutiis, M. A.
Fulcheri, M.
Tete, S.
Galzio, R.
Salini, V.
Caraffa, A.
Antinolfi, P.
Frydas, I.
Sabatino, G.
Shaik Dasthagirisaheb, Y. B.
Pandolfi, Franco (ORCID:0000-0001-8799-8173)
Publication Year :
2011

Abstract

IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support a role for IL-18 in inflammation, allergy and immune diseases.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1104998488
Document Type :
Electronic Resource